Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 400/80mg | ||||
360 pill | 400/80mg | $150.99 | $0.42 | |
270 pill | 400/80mg | $115.99 | $0.43 | |
180 pill | 400/80mg | $84.99 | $0.47 | |
120 pill | 400/80mg | $60.99 | $0.51 | |
90 pill | 400/80mg | $48.99 | $0.54 | |
60 pill | 400/80mg | $34.99 | $0.59 | |
30 pill | 400/80mg | $19.99 | $0.65 | |
Dosage: 800/160mg | ||||
360 pill | 800/160mg | $399.99 | $1.11 | |
180 pill | 800/160mg | $210.99 | $1.17 | |
120 pill | 800/160mg | $149.99 | $1.25 | |
90 pill | 800/160mg | $117.99 | $1.31 | |
60 pill | 800/160mg | $82.99 | $1.39 | |
30 pill | 800/160mg | $42.99 | $1.44 | |
20 pill | 800/160mg | $29.99 | $1.48 | |
10 pill | 800/160mg | $14.99 | $1.50 |

Trimethoprim Description
Introduction to Trimethoprim
Trimethoprim is a widely used antibiotic that belongs to the class of drugs known as dihydrofolate reductase inhibitors. It is primarily prescribed to treat bacterial infections, especially urinary tract infections (UTIs). This medication works by inhibiting bacterial DNA synthesis, which ultimately leads to the death of the bacteria. Its potent action and relatively narrow spectrum of activity make it a popular choice among healthcare providers.
How Trimethoprim Works
The effectiveness of Trimethoprim stems from its ability to block the production of tetrahydrofolic acid, a critical component in bacterial DNA synthesis. By targeting the enzyme dihydrofolate reductase, it prevents bacteria from multiplying and spreading the infection. This mechanism ensures that the medication is highly selective for bacteria and less likely to affect human cells, although some side effects can still occur. Usually, it is used in combination with sulfamethoxazole for a synergistic effect, but it can also be prescribed alone for specific conditions.
Uses and Effectiveness
Meximum effectiveness of Trimethoprim can be observed in urinary tract infections, especially uncomplicated cases caused by bacteria such as Escherichia coli. Additionally, it may be prescribed for respiratory infections, gastrointestinal infections, and certain skin infections. The medication is often praised for its rapid action and ease of use, with many patients experiencing relief within a few days of starting therapy. Proper adherence to the prescribed dosage and duration enhances its success rate and minimizes the risk of resistance.
Potential Side Effects
Like many antibiotics, Trimethoprim may cause side effects in some individuals. Common adverse reactions include nausea, vomiting, loss of appetite, and gastrointestinal discomfort. Some patients may develop allergic reactions, such as rash or itching. Rare but serious side effects can involve blood disorders like leukopenia or thrombocytopenia, especially with prolonged use. Skin sensitivities such as photosensitivity are also possible, so patients are advised to avoid excessive sunlight exposure while taking this medication. It is important to consult a healthcare provider if any unusual symptoms occur during treatment.
Precautions and Interactions
Before starting Trimethoprim, patients should inform their healthcare provider of any existing health conditions, especially kidney or liver problems and blood disorders. The medication may interact with other drugs, including certain diuretics, methotrexate, and other antibiotics, which can alter its effectiveness or increase side effects. Pregnant and breastfeeding women should use this medication only under medical supervision, as safety data are limited. Regular monitoring through blood tests may be required during extended therapy to detect potential blood abnormalities.
Usage Tips and Final Considerations
To get the most benefit from Trimethoprim, it is crucial to follow the prescribed dosage and complete the full course of treatment, even if symptoms improve before the medication is finished. Skipping doses or discontinuing early can lead to bacterial resistance and treatment failure. Drinking plenty of water helps flush out bacteria and can reduce the likelihood of side effects like kidney stones. If any adverse reactions or signs of allergic response appear, immediate medical attention should be sought. Overall, when used responsibly and under proper guidance, Trimethoprim remains an effective option for combating bacterial infections.