Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 0.25mcg | ||||
180 cap | 0.25mcg | $235.00 | $1.31 | |
120 cap | 0.25mcg | $175.79 | $1.47 | |
90 cap | 0.25mcg | $148.88 | $1.65 | |
60 cap | 0.25mcg | $123.77 | $2.06 | |
30 cap | 0.25mcg | $82.51 | $2.74 | |
Dosage: 0.5mcg | ||||
180 cap | 0.5mcg | $297.79 | $1.65 | |
120 cap | 0.5mcg | $217.06 | $1.81 | |
90 cap | 0.5mcg | $177.59 | $1.97 | |
60 cap | 0.5mcg | $132.74 | $2.21 | |
30 cap | 0.5mcg | $87.89 | $2.92 |

Alfacalcidol Description
Overview of Alfacalcidol
Alfacalcidol is a synthetic form of vitamin D, commonly used in the management of various conditions related to calcium and phosphate metabolism. Its primary function is to help regulate calcium absorption in the gut and improve bone mineralization. This medication is particularly beneficial for individuals with specific deficiencies or disorders affecting bone health, including osteoporosis, chronic kidney disease, and certain types of rickets.
How Does Alfacalcidol Work?
Alfacalcidol is a prodrug that is converted in the body to the active form of vitamin D, known as calcitriol. Once activated, it enhances intestinal absorption of calcium and phosphate, minerals essential for healthy bone formation. Moreover, it influences bone turnover and mineralization directly, aiding in the treatment of conditions characterized by weakened bones. Its mechanism helps compensate for the body's impaired ability to produce active vitamin D, which is common in patients with kidney impairment.
Uses and Benefits
This medication is widely used for patients suffering from secondary hyperparathyroidism, a common complication in chronic kidney disease. It also plays a role in managing osteoporosis, especially when combined with other medications. In addition, Alfacalcidol is prescribed for managing rickets, osteomalacia, and other metabolic bone diseases where vitamin D deficiency contributes to weakening bones. Patients often see improvements in bone density and a reduction in fractures when adhering to their treatment regimen with Alfacalcidol.
Administration and Dosage
Alfacalcidol is usually administered orally in the form of capsules or drops. The dosage depends on the patient's specific condition, age, and response to treatment. Physicians typically start with a low dose and gradually adjust it to achieve optimal results while avoiding potential side effects. It’s crucial to follow medical advice precisely and not modify the dosage without consulting a healthcare professional. Regular blood tests are often necessary to monitor calcium and phosphate levels during therapy.
Possible Side Effects
While generally well-tolerated, Alfacalcidol can cause side effects in some individuals. The most common adverse effect is hypercalcemia, which manifests as nausea, vomiting, weakness, or confusion. Elevated calcium levels can lead to kidney stones or calcification of soft tissues if not properly managed. Less frequently, some users might experience gastrointestinal discomfort or allergic reactions. It is essential to report any unusual symptoms to a healthcare provider promptly.
Precautions and Interactions
Before starting Alfacalcidol, patients should inform their doctor about any existing health conditions, especially kidney problems, hypercalcemia, or cardiovascular diseases. The medication may interact with other drugs such as thiazide diuretics, which can increase calcium levels, or certain anticonvulsants that affect vitamin D metabolism. Regular monitoring is vital to avoid mineral imbalances and side effects. Additionally, patients should adhere meticulously to dietary guidelines to prevent excessive calcium intake.
Conclusion
Alfacalcidol is an effective tool in managing serious bone and mineral disorders related to vitamin D deficiency. Its ability to improve calcium absorption and support bone health makes it a valuable medication in specialized treatments. Proper medical supervision and adherence to prescribed dosages are essential to maximize benefits and minimize risks associated with its use. For individuals with specific health needs, Alfacalcidol can significantly enhance quality of life by promoting stronger bones and better mineral balance.