Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 10mg | ||||
240 pill | 10mg | $369.99 | $1.54 | |
180 pill | 10mg | $278.99 | $1.55 | |
120 pill | 10mg | $187.99 | $1.57 | |
90 pill | 10mg | $148.99 | $1.65 | |
60 pill | 10mg | $103.99 | $1.73 | |
30 pill | 10mg | $55.99 | $1.85 | |
10 pill | 10mg | $20.99 | $2.12 | |
Dosage: 20mg | ||||
120 pill | 20mg | $342.99 | $2.86 | |
90 pill | 20mg | $261.99 | $2.91 | |
60 pill | 20mg | $184.99 | $3.09 | |
30 pill | 20mg | $100.99 | $3.36 | |
10 pill | 20mg | $36.99 | $3.71 |

Leflunomide Description
Overview of Leflunomide
Leflunomide is a prescription medication commonly used in the treatment of autoimmune diseases, particularly rheumatoid arthritis. It belongs to a class of drugs known as disease-modifying antirheumatic drugs (DMARDs). This medication works by suppressing the immune response that causes inflammation and joint damage in autoimmune conditions. Its primary function is to reduce symptoms such as pain, swelling, and stiffness, helping to improve the overall quality of life for patients suffering from chronic inflammatory diseases.
Mechanism of Action
Leflunomide acts by inhibiting the enzyme dihydroorotate dehydrogenase, which plays a key role in pyrimidine synthesis. By reducing the production of pyrimidines, Leflunomide effectively limits the proliferation of activated lymphocytes, which are central to the autoimmune process. This suppression of lymphocyte activity helps decrease inflammation and prevents further joint destruction. The medication's immunomodulatory effects make it an effective option when other treatments, like non-steroidal anti-inflammatory drugs (NSAIDs), fail to control symptoms adequately.
Benefits and Effectiveness
Patients taking Leflunomide often experience a significant reduction in joint pain and swelling after several weeks of therapy. Its ability to slow disease progression is well-documented, making it a cornerstone in the management of rheumatoid arthritis. Many users report improved joint mobility and a decrease in morning stiffness, leading to enhanced daily functioning. Due to its long-lasting effects, Leflunomide is usually taken once daily, providing convenience and consistent disease control.
Possible Side Effects
Like all medications, Leflunomide can cause side effects. Common reactions include gastrointestinal issues such as diarrhea, nausea, and abdominal pain. Some individuals may experience elevated blood pressure, hair loss, or skin rashes. Rare but serious side effects can involve liver toxicity, blood disorders, and increased susceptibility to infections. Because of potential adverse effects, regular monitoring through blood tests is recommended during treatment.
Precautions and Interactions
Before starting Leflunomide, patients should disclose their full medical history, especially liver conditions or immune system disorders. It's important to avoid pregnancy while on this medication due to potential teratogenic effects. Patients taking other immunosuppressants or medications with hepatotoxic potential should consult their healthcare provider, as interactions can increase risks or diminish efficacy. Alcohol consumption should be limited to reduce strain on the liver, and routine liver function tests are vital during therapy to detect early signs of toxicity.
Availability and Dosage
Leflunomide is available through online pharmacies, but it must be prescribed by a healthcare professional. The typical starting dose is 100 mg daily for the first three days, followed by a maintenance dose of 20 mg once daily. The dosage may be adjusted based on individual response and tolerance. Patients should adhere strictly to the prescribed dosing schedule and attend regular medical check-ups to assess treatment progress.
Customer Experiences and Reviews
Many users report significant improvement in their symptoms after initiating Leflunomide therapy. They often mention a noticeable reduction in joint pain and swelling within the first few months. Some patients appreciate the once-daily dosing, which enhances adherence. However, a subset of users experiences mild side effects like stomach upset or hair thinning, which usually resolve over time or with dosage adjustments. Overall, patient reviews highlight Leflunomide's effectiveness in managing chronic disease symptoms when used under proper medical supervision.